| 產(chǎn)品詳情 |
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| Product Name | (±)8(9)-EET |
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| Description | Purity >98%. (±)8(9)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid . (±)8(9)-EET is a major cytochrome P450 (CYP450) metabolite in the renal cortex. It activates PPARAlpha in HEK293 cells when used at a concentration of 1 μM but inhibits NF-KappaB activity induced by IL-1Beta in a PPARAlpha-dependent and -independent fashion. It is also a substrate of COX-1 and COX-2, as measured by oxygen consumption and product formation assays when used at a concentration of 50 μM. (8S,9R)-EET (1 μg/kg), but not (8R,9S)-EET, reduces the glomerular filtration rate (GFR) through COX-dependent pre-glomerular vasoconstriction in rats. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (±)8,9-epoxy-5Z,11Z,14Z-eicosatrienoic acid, (±)8,9-EpETrE |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H5541 |
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| Price | |
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| Order / More Info | (±)8(9)-EET from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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