| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | 2-(Phosphonomethyl)-pentanedioic Acid |
|---|
| Description | A potent inhibitor of GCP II/NAALADase (Ki = 98 pM for release of glutamate from the NAALADase peptide substrate NAAG); selective for GCP II/NAALADase over a panel of 100 receptors, transporters, ion channels, and enzymes at a concentration of 10 μM; neuroprotective against hypoxia (EC50 = 8.4 μM) in neuron-enriched primary cultures from rat embryo cerebellum; reduces neuronal cell death induced by middle cerebral artery occlusion in rats; blocks the conditioned place preference response to cocaine in male rats (100 mg/kg); reduces the number of flinches induced by formalin injection into the footpad of mice (10 μg per animal); decreases severity and delays onset of EAE in mice, |
|---|
| Size | 1 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 2-PMPA |
|---|
| Gene, Accession, CAS # | CAS: 173039-10-6 |
|---|
| Catalog # | 21916-1 |
|---|
| Price | |
|---|
| Order / More Info | 2-(Phosphonomethyl)-pentanedioic Acid from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|