| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | Recombinant Mouse CCL19 (MIP-3β) (carrier-free) |
|---|
| Description | CCL19 is a CC chemokine expressed in lymph nodes. CCL19 is only 32% identical to CCL21 at the amino acid level; nevertheless, these chemokines bind to the same receptor: CCR7. CCL19 is not expressed in high endothelial venules (HEV) as CCL21, but CCL19 is transcytosed in HEV. It has been described that CCL19 binds to CCX-CKR and CRAM-B receptors. These two receptors are members of the non classical chemokine receptor family which, in addition, includes D6, DARC, and CXCR7. CCX-CKR has been suggested to be a scavenging receptor for CCL19, and CRAM-B receptor might be responsible for the transcytosis in HEV for CCL19. In addition, CRAM recycles constitutively, and can internalize CCL19 within a few minutes, suggesting an implication in the regulation of immune responses and homing processes. |
|---|
| Size | 100 μg |
|---|
| Concentration | n/a |
|---|
| Applications | BA |
|---|
| Other Names | EBI1 ligand chemokine (ELC), Macrophage inflammatory protein-3-beta (MIP-3b), Small inducible cytokine subfamily A, member 19 (SCYA19), MIP3b, MIP3 beta, MIP 3 beta |
|---|
| Gene, Accession, CAS # | Gene ID: 24047 |
|---|
| Catalog # | 587806 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Mouse CCL19 (MIP-3β) (carrier-free) from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|