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| Antigenic Specificity | NALP4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor? 555 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NALP4 Polyclonal Antibody, Alexa Fluor? 555 Conjugated. ? Target Background: May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors. Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, and its subsequent degradation. Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, suggesting that it operates at a point of convergence in these two cytokine signaling pathways. |
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| Immunogen | KLH conjugated synthetic peptide derived from human NALP4. Immunogen Range: 370-420/994 |
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| Other Names | NACHT, LRR and PYD domains-containing protein 4; Cancer/testis antigen 58; CT58; PAAD and NACHT-containing protein 2; PAN2; PYRIN and NACHT-containing protein 2; PYRIN-containing APAF1-like protein 4; PYPAF4; Ribonuclease inhibitor 2; NLRP4; NALP4; RNH2 |
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| Gene, Accession # | Gene ID: 147945, SwissProt: Q96MN2 |
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| Catalog # | bs-6855R-A555 |
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| Price | |
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| Order / More Info | NALP4 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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