| 產(chǎn)品詳情 |
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| Product Name | Recombinant Human BRCA1-associated protein (BRAP) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 69.3kDa. Full Length: 1-592aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a Cytoplasmic domain retention protein with a role in regulating nuclear transport. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | BRAP2Impedes mitogenic signal propagation; IMPRING finger protein 52Renal carcinoma antigen NY-REN-63 |
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| Gene, Accession, CAS # | BRAP, UniProt: Q7Z569 |
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| Catalog # | RPC25443 |
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| Order / More Info | Recombinant Human BRCA1-associated protein (BRAP) from BIOMATIK |
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| Product Specific References | n/a |
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