| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD193 |
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| Clone | 5E8 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b, κ |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), IHC-P |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human CD193 (CCR3). CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types. |
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| Immunogen | n/a |
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| Other Names | CC CKR3, MIP1-alpha receptor like-2, eotaxin receptor, CCR3 |
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| Gene, Accession # | Gene ID: 1232 |
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| Catalog # | 310702 |
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| Price | |
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| Order / More Info | CD193 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 21051556 |
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| 產(chǎn)品資料 |
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