| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | MRK 016 |
|---|
| Description | GABAA receptor inverse agonist selective for the α5-subtype (EC50 = 3 nM). Exhibits affinity at benzodiazepine binding site of recombinant human GABAA receptors (Ki values are 0.77 nM, 0.83 nM, 0.85 nM and 1.4 nM for α3-, α1-, α2-, and α5-containing respectively). Increases long-term potentiation (LTP) in mouse hippocampal slices. Exhibits no anxiogenic or proconvulsant activity. Purity 98%. MW (observed): 368.39 |
|---|
| Size | 50 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 3-(1,1-Dimethylethyl)-7-(5-methyl-3-isoxazolyl)-2-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-pyrazolo[1,5-d][1,2,4]triazine |
|---|
| Gene, Accession, CAS # | CAS: 342652-67-9 |
|---|
| Catalog # | 3817/50 |
|---|
| Price | |
|---|
| Order / More Info | MRK 016 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 28275719 |
|---|
| 產(chǎn)品資料 |
|
|