| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | Caspase-1 |
|---|
| Clone | 5B10 |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG2a |
|---|
| Format | purified |
|---|
| Size | 25 μg |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot (WB), IHC |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Purified anti-Caspase-1. Caspase -1 plays a vital role in cleaving the inactive procytokine pro-IL-1 beta to generate the active 17 kd mature form of IL-1beta, a key mediator of inflammation. Active caspase-1 (ICE) is derived a single proenzyme of 45 Kd. An active ICE comprises two subunits of P20 and two subunits of P10 after removal a large amino-terminal pro-domain and a small linker peptide. Caspase-1 is reported to be involved in CD95- mediated apoptosis. Four alternatively spliced variants of caspase-1 have been reported, with mw ranging from 30-48 kd. |
|---|
| Immunogen | Bacterial fusion protein (p20) |
|---|
| Other Names | ICE |
|---|
| Gene, Accession # | Gene ID: 834 |
|---|
| Catalog # | 645101 |
|---|
| Price | |
|---|
| Order / More Info | Caspase-1 Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|