| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | Damnacanthal |
|---|
| Description | Potent inhibitor of p56lck tyrosine kinase activity (IC50 = 17 nM for inhibition of autophosphorylation). Displays 7- to 20-fold selectivity over p59fyn and p60src tyrosine kinases, > 40-fold selectivity over c-ErbB2, EGF- and insulin-receptor tyrosine kinases, and > 100-fold selectivity over PKA and PKC. Mobilizes intracellular Ca2+ in dermal fibroblasts and inhibits Ras function. Also inhibits LIMK1/2, as well as migration and invasion of breast cancer cells in vitro. Purity 98%. MW (observed): 282.25 |
|---|
| Size | 1 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 9,10-Dihydroxy-3-hydroxy-1-methoxy-9,10-dioxo-2-anthracenecarboxaldehyde |
|---|
| Gene, Accession, CAS # | CAS: 477-84-9 |
|---|
| Catalog # | 1936/1 |
|---|
| Price | |
|---|
| Order / More Info | Damnacanthal from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|