| 產(chǎn)品詳情 |
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| Antigenic Specificity | MAPK3 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b, k |
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| Format | purified |
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| Size | 100ul, 50ul |
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| Concentration | n/a |
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| Applications | ELISA, WB, ICC/IF |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mitogen-activated protein kinase (MAPKs) are a widely conserved family of serine/threonine kinase involved in many cellular programs such as cell proliferation, differentiation, motility, and death. MAPK3 (ERK1) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is on important target in the diagnosis and treatment of cancer. Upon stimulation, a sequential three-part protein kinase cascade is initiated, consisting of a MAP kinase kinase kinase (MAPKKK or MAP3K), a MAP kinase kinase (MAPKK or MAP2K), and a MAP kinase (MAPK). Multiple p44/42 MAP3Ks have been identified, including members of the Raf family as well as Mos and Tpl2/Cot. MEK1 and MEK2 are the primary MAPKKs in this pathway. |
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| Immunogen | Recombinant human MAPK3 protein (1-137aa) purified from E. coli |
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| Other Names | Mitogen-activated protein kinase 3, ERK1, HS44KDAP, HuMKER1A, P44ERK1, P44MAPK, PRKM3, MAP kinase3, Mitogen-activated protein kinase 3 |
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| Gene, Accession # | NP 002737.2 |
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| Catalog # | ATGA0191 |
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| Price | |
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| Order / More Info | MAPK3 Antibody from ATGen |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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