| 產(chǎn)品詳情 |
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| Antigenic Specificity | AKT1 |
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| Clone | 2147 |
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| Host Species | Human |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ELISA, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Human Anti-AKT1 Monoclnal Antibody (2147). Provided herein is a human monoclonal antibody against Human AKT1. The antibody, clone 2147, can be used for immunoassay techniques, such as ELISA and WB. AKT1 is a serine-threonine protein kinase, which is catalytically inactive in serum-starved primary and immortalized fibroblasts. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. |
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| Immunogen | Human AKT1 (Val106 - Ala480) fusion protein. The antigen contains the complete kinase domain (aa 150-408) but not the N-terminal PH domain. Amino acid residues 106-480, MW 77.8 kDa |
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| Other Names | AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA |
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| Gene, Accession # | Gene ID: 207, UniProt: P31749 |
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| Catalog # | CBMAB-0933-YC |
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| Price | |
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| Order / More Info | AKT1 Antibody from CREATIVE BIOLABS |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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