| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | MK-0752 |
|---|
| Description | MK-0752 is a potent and reversible inhibitor of γ-secretase, reducing the cleavage of APP to Aβ40 in human neuroblastoma SH-SY5Y cells (IC50 = 5 nM). Through its effects on the Notch pathway, MK-0752 reduces the number of breast cancer stem cells in tumorgrafts, enhancing the efficacy of the chemotherapy drug docetaxel (Cat. No. 2232) in mice with breast cancer tumors. MW: 442.9. Purity ≥98% by HPLC |
|---|
| Size | 1 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 3-[4-(4-chlorophenyl)sulfonyl-4-(2,5-difluorophenyl)cyclohexyl]propanoic acid |
|---|
| Gene, Accession, CAS # | CAS: 471905-41-6 |
|---|
| Catalog # | B1980-1 |
|---|
| Price | |
|---|
| Order / More Info | MK-0752 from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|