| 產品詳情 |
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| Product Name | VX 680 |
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| Description | High affinity and selective Aurora kinase inhibitor (Ki values are 0.6, 5 and 18 nM for Aurora A, Aurora C and Aurora B, respectively). Also exhibits affinity for FLT-3 and Abl. Exhibits selectivity for Aurora kinase over 190 other protein kinases. Inhibits proliferation and induces apoptosis in a number of cancer cell lines in vitro. Reduces tumor size in leukemia and colon cancer cell xenografts in mice. Purity 98%. MW (observed): 464.59 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[4-[[4-(4-Methyl-1-piperazinyl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]thio]phenyl]cyclopropanecarboxamide. MK 0457, Tozasertib |
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| Gene, Accession, CAS # | CAS: 639089-54-6 |
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| Catalog # | 5907/50 |
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| Price | |
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| Order / More Info | VX 680 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 產品資料 |
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