| 產(chǎn)品詳情 |
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| Product Name | IWP 2 |
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| Description | Inhibitor of Wnt processing and secretion. Inactivates PORCN, a membrane-bound O-acyltransferase (MBOAT), and selectively inhibits palmitoylation of Wnt. Blocks Wnt-dependent phosphorylation of Lrp6 receptor and Dvl2, and β-catenin accumulation. Suppresses self-renewal in R1 embryonic stem cells. Purity 98%. MW (observed): 466.6 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide |
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| Gene, Accession, CAS # | CAS: 686770-61-6 |
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| Catalog # | 3533/10 |
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| Order / More Info | IWP 2 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23423383, 24291815, 24968096, 25333967, 25360795, 25454631, 25654758, 25706534, 25915127, 25980672, 26139150, 26493500, 26554899, 26695765, 26969725, 28332498, 28777944, 29281831, 29996941 |
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