| 產(chǎn)品詳情 |
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| Product Name | C3 |
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| Description | Selective microsomal prostaglandin E synthase 1 (mPGES-1) inhibitor (IC50 values are 90 and 900 nM for rat and human mPGES-1, respectively). Displays selectivity for mPGES-1 over COX-1, COX-2, PGIS, hPGDS and iPGDS (% inhibition values are 15, 18, 0, 0 and 60 % inhibition at 50 μM, respectively). Reduces PGE2 production in vitro and in a localized inflammation animal model. Elevates CD80 expression by tumor associated phagocytes in vitro. Also decreases vascular contractility, in ex vivo human vessels. Purity 98%. MW (observed): 382.54 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-Cyclopentyl-1-[5,6-dimethyl-1-(1-methylethyl)-1H-benzimidazol-2-yl]-4-piperidinecarboxamide |
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| Gene, Accession, CAS # | CAS: 1268709-57-4 |
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| Catalog # | 5957/10 |
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| Order / More Info | C3 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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