| 產品詳情 |
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| Antigenic Specificity | PXR |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 5 μg/mL, Western Blot: 0.2-1 μg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PXR Polyclonal Antibody. This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. |
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| Immunogen | n/a |
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| Other Names | Nuclear receptor subfamily 1, group I member 2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR |
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| Gene, Accession # | Entrez: 8856; Uniprot: O75469 |
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| Catalog # | PA5-41170 |
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| Price | |
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| Order / More Info | PXR Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 產品資料 |
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