| 產(chǎn)品詳情 |
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| Antigenic Specificity | ZO-1 |
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| Clone | ZO1-1A12 |
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| Host Species | Mouse |
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| Reactive Species | canine, human |
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| Isotype | IgG1, kappa |
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| Format | fluorescein (FITC) conjugate |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | ELISA: 0.1-1.0 μg/mL, Immunocytochemistry: 1-10 μg/mL, Immunofluorescence: 1-10 μg/mL, Western Blot: 1-2 μg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ZO-1 Monoclonal Antibody (ZO1-1A12), FITC. ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding |
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| Immunogen | n/a |
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| Other Names | ZO-1, tight junction protein ZO-1, zona occludens 1, zona occludens protein 1, zonula occludens 1 protein, zonula occludens protein 1 |
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| Gene, Accession # | Entrez: 403752, 7082; Uniprot: O97758, Q07157 |
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| Catalog # | 33-9111 |
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| Price | |
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| Order / More Info | ZO-1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12697723, 15623527, 15880438, 17852186, 18308303, 19526522, 20035913, 20713173, 21029292, 21191089, 21909099, 21937955, 22639968, 22682521, 23248771, 23492904, 23546604, 23565266, 24169556, 24755297, 24873859, 25456071, 26664249, 27336173 |
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