| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | ZO-1 |
|---|
| Clone | R26.4C |
|---|
| Host Species | Rat |
|---|
| Reactive Species | canine, mouse, rat |
|---|
| Isotype | IgG2a, kappa |
|---|
| Format | purified |
|---|
| Size | 25 μg |
|---|
| Concentration | n/a |
|---|
| Applications | Immunocytochemistry: 10 μg/mL, Immunofluorescence: 10 μg/mL, Immunohistochemistry (Frozen): 10 μg/mL, Western Blot: Assay-Dependent |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | ZO-1 Monoclonal Antibody (R26.4C), eBioscience?. ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript varia |
|---|
| Immunogen | n/a |
|---|
| Other Names | DKFZp686M05161, MGC133289, ZO-1 |
|---|
| Gene, Accession # | Entrez: 21872, 292994, 403752; Uniprot: O97758, P39447 |
|---|
| Catalog # | 14-9776-80 |
|---|
| Price | |
|---|
| Order / More Info | ZO-1 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|