| 產(chǎn)品詳情 |
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| Antigenic Specificity | AKT1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 1 mL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: Assay dependent, Immunoprecipitation: Assay dependent, Western Blot: Assay dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | AKT1 Polyclonal Antibody. AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively modulates its phosphatase activity preventing dephosphorylation of the i |
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| Immunogen | n/a |
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| Other Names | AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA |
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| Gene, Accession # | Entrez: 11651, 207, 24185; Uniprot: P31749, P31750, P47196 |
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| Catalog # | PA1-22099 |
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| Price | |
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| Order / More Info | AKT1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 28466269 |
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| 產(chǎn)品資料 |
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