| 產(chǎn)品詳情 |
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| Antigenic Specificity | AKT1 |
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| Clone | 9Q7 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG3, kappa |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | AKT1 Monoclonal Antibody (9Q7). AKT also known as protein kinase B (PKB) or RAS-alpha, is an ubiquitous serine/threonine kinase that plays an important role in diverse biological responses such as regulation of metabolism, cell survival and growth by phosphorylating multiple proteins. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9. The AKT pathway is a major target for cancer drug discovery. |
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| Immunogen | n/a |
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| Other Names | AKT, AKT1 kinase, C-AKT, EC 2.7.11.1, PKB, PKB-alpha, Protein kinase B, RAC, RAC-PK-alpha, RAC-alpha serine/threonine kinase, kinase Akt1 |
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| Gene, Accession # | Entrez: 11651, 207, 24185; Uniprot: P31749, P31750, P47196 |
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| Catalog # | AHO1112 |
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| Price | |
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| Order / More Info | AKT1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 26900867, 27239960 |
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| 產(chǎn)品資料 |
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