| 產(chǎn)品詳情 |
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| Antigenic Specificity | Caspase-9 (Active) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 μg |
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| Concentration | 0.2 mg/ml |
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| Applications | Western blot, Immunoprecipitation |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase-9 (Active) Antibody. Caspases are synthesized as inactive pro-enzymes that are processed to active form in cells undergoing apoptosis. Caspase-9 is an important member of the caspase family. Upon induction of apoptosis, Cytochrome c released from mitochondria associates with pro-caspase-9 (47 kDa) and Apaf-1. The complex processes pro-caspase-9 into a large subunit (37 kDa/17 kDa) and a small subunit (10 kDa). Cleaved caspase-9 further processes other caspases including caspase-3 and caspase-6, to initiate a caspase cascade leading to apoptosis. The affinity purified antibody recognizing the active forms of caspase-9 provides a new tool for identifying apoptotic cell populations in both tissue sections and cultured cells. |
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| Immunogen | Synthetic peptide mapping to the N-terminus adjacent to Asp330 of human caspase-9 |
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| Other Names | CASP-9, EC 3.4.22.62, ICE-like apoptotic protease 6,ICE-LAP6,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3, Apaf-3 |
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| Gene, Accession # | Gene ID: 12371, Accession: P55211 |
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| Catalog # | 3149-100 |
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| Price | |
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| Order / More Info | Caspase-9 (Active) Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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