| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | Rosiglitazone |
|---|
| Description | A thazolidinedione agonist of PPARγ; binds to the LBD of PPARγ (Kd = 43 nM); selectively activates chimeras containing the LBDs of PPARγ over PPARα and PPARδ in a cell-based reporter assay at 10 μM; activates full-length PPARγ1 and PPARγ2 in a reporter assay (EC50s = 30 and 100 nM, respectively); induces differentiation of C3H10T1/2 stem cells to adipocytes at 1 μM; decreases HbA1c and fasting blood glucose levels in a rat model of type 2 diabetes induced by STZ and a high-carbohydrate/high-fat diet at 4 mg/kg; inhibits increases in contusion volume, macrophage infiltration and activation of microglia, and expression of IL-6, MCP1, ICAM1, caspase-3, and Bax in mouse cerebral cortex in a model of traumatic brain injury induced by controlled cortical impact at 6 mg/kg |
|---|
| Size | 100 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | BRL 49653 |
|---|
| Gene, Accession, CAS # | CAS: 122320-73-4 |
|---|
| Catalog # | 71740-100 |
|---|
| Price | |
|---|
| Order / More Info | Rosiglitazone from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|