| 產(chǎn)品詳情 |
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| Antigenic Specificity | RanBP3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor? 750 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RanBP3 Polyclonal Antibody, Alexa Fluor? 750 Conjugated. ? Target Background: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 |
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| Immunogen | KLH conjugated synthetic peptide derived from human RanBP3. Immunogen Range: 450-500/567 |
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| Other Names | Ran-binding protein 3; RanBP3 |
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| Gene, Accession # | Gene ID: 8498, SwissProt: Q9H6Z4 |
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| Catalog # | bs-20113R-A750 |
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| Price | |
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| Order / More Info | RanBP3 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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