| 產(chǎn)品詳情 |
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| Antigenic Specificity | Importin beta-1 |
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| Clone | 3E9 |
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| Host Species | Mouse |
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| Reactive Species | bovine, canine, human, mouse, porcine, rat |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1 μg/test, Immunocytochemistry: 1:1000, Immunofluorescence: 1:1,000, Immunoprecipitation: Assay dependent, Inhibition Assays: Assay Dependent, Western Blot: 1:5,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Importin beta-1 Monoclonal Antibody (3E9). The accumulation of proteins in the nucleus is mediated by short sequences of basic amino acids called nuclear localization sequences (NLSs). These sequences are necessary and sufficient to direct a protein or inert carrier to the nuclear interior. Nuclear protein import is accomplished by two sequential, energy dependent events. The first step, docking at the nuclear pore complex, requires a 54/56 kDa nuclear localization signal receptor (a-karyopherin, importin-a, SRP-a) and the nuclear transport factor p97 (NTF97, b-karyopherin, importin-b). The second step, translocation across the nuclear envelope (NE), requires the GTP-binding protein, Ran/TC4. |
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| Immunogen | n/a |
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| Other Names | NTF97, Karyopherin, Importin Beta, Nuclear Transport Factor p97, karyopherin beta 1 |
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| Gene, Accession # | Entrez: 100518449, 16211, 24917, 3837, 491042, 507804; Uniprot: P52296, P70168, Q14974 |
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| Catalog # | MA3-070 |
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| Price | |
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| Order / More Info | Importin beta-1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10393926, 10848617, 11257130, 11850439, 12672698, 15761260, 16704975, 16730000, 16801526, 17786044, 18635968, 20174585, 21285245, 21832065, 22718973, 9585406 |
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