| 產(chǎn)品詳情 |
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| Antigenic Specificity | WNT7A |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | lyophilized |
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| Applications | Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 0.5 μg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | WNT7A Polyclonal Antibody. Wnt proteins constitute a family of secreted glyocoproteins that activate signal transduction pathways to mediate tissue homeostasis, cell fate, cell proliferation, and self-renewal. The canonical signaling pathway is initiated upon Wnt binding to a Frizzled family receptor and an LRP5/LRP6 coreceptor, which leads to activation of the beta-catenin cascade. Non-canonical Wnt signals are activated by binding to a Frizzled family receptor and ROR2 coreceptor. Extensive research has shown that deregulation of these pathways or its components can lead to cancer. Human Wnt-1 is encoded as a 370 amino acid precursor that, upon secretion, is cleaved into a 343 amino acid (42 kDa) mature form. At the amino acid level, matu |
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| Immunogen | n/a |
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| Other Names | Protein Wnt-7a, WNT7A |
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| Gene, Accession # | Entrez: 114850, 22421, 7476; Uniprot: O00755, P24383 |
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| Catalog # | PA5-80231 |
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| Price | |
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| Order / More Info | WNT7A Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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