| 產(chǎn)品詳情 |
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| Antigenic Specificity | IL-21 |
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| Clone | 7H20-I19-M3 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1, κ |
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| Format | biotin conjugate |
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| Size | 50 μg |
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| Concentration | n/a |
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| Applications | Western Blot (WB), Immunofluorescence Microscopy (IF) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Biotin anti-human/mouse IL-21. Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset and has pleiotropic effects on both innate and adaptive immune responses.? These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells.? It can also be proapoptotic for B cells and NK cells.? Recent studies have shown that IL-21 is also an autocrine cytokine that potently induces T(H)17 differentiation and suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases. |
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| Immunogen | Recombinant full length human IL-21 |
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| Other Names | Interleukin 21 |
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| Gene, Accession # | Gene ID: 59067, 60505 |
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| Catalog # | 514303 |
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| Price | |
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| Order / More Info | IL-21 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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