| 產(chǎn)品詳情 |
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| Antigenic Specificity | LAMP-2A |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | ELISA: 0.1-1 μg/mL, Inhibition Assays: Assay Dependent, Western Blot: 0.1-1 μg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LAMP-2A Polyclonal Antibody (AMC2). Lysosome-Associated Membrane Protein 2 (LAMP-2) has been demonstrated to be involved in the direct uptake of cytosolic proteins in lysosomes and also participates in the endocytic pathway. LAMP-2 is used to monitor a very selective form of autophagy called chaperone-mediated autophagy. The protein is localized mainly to lysosomes; however, under certain conditions, it can also be detected in the plasma membrane. Interestingly, the level of LAMP-2 protein expressed on the surface of tumor cells has been found to correlate with the tumor's metastatic potential. In lysosomes, LAMP-2 is localized to the lysosomal lumen and has a structure comprised of a large N-terminal intra-lysosomal domain. It is inserted |
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| Immunogen | n/a |
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| Other Names | Igp96, LAMP-2a, LAMP-2 Variant A, LAMP-2 Isoform 2A, CD107b, LAMP-2, LAMP2, CD107 antigen-like family member B, lysosome-associated membrane glycoprotein 2, |
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| Gene, Accession # | Entrez: 16784, 24944; Uniprot: P17046, P17047 |
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| Catalog # | 51-2200 |
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| Price | |
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| Order / More Info | LAMP-2A Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 15331763, 15644317, 15883160, 18848948, 19349362, 19840943, 20388541, 22426402, 22800931, 22804716, 22892312, 24569882, 25160620, 25855184, 25891649, 25961502, 26693174, 26912421, 27061426, 27689619, 28123102, 28432355, 8662539, 9693362 |
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