| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD274 Molecule (CD274) |
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| Clone | MIH3 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | biotin conjugate |
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| Size | 1 mL |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Programmed death ligand 1 (PD-L1, also known as CD274/B7-H1), a member of B7 family was identified by searching for molecules that share homology with the immunoglobulin V and C domains of B7-1 and B7-2 among the human cDNA expressed sequence tags in the National Center for Biotechnology Information database. PD-L1 is a ligand for programmed death 1 (PD-1) which belongs to the CD28/CTLA4 subfamily. Although in vitro study indicated that the cross-linking of PD-1 by PD-L1 leads to down-regulation of T-cell responses, some studies have shown that T cells stimulated with low levels of anti-CD3 and immobilized PD-L1-Ig were activated, proliferation and production of IFN-γ, GM-CSF and IL-10 from the T cells were enhanced.Synonyms: B7 homolog 1, B7H1, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, Programmed death ligand 1 |
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| Immunogen | Full-length human PD-L1 transfected L cells |
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| Other Names | A530045L16Rik|B7h1|Pdcd1l1|Pdcd1lg1|Pdl1|B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1|RGD1566211 |
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| Gene, Accession # | Gene ID: 29126 |
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| Catalog # | ABIN2853592 |
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| Price | |
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| Order / More Info | CD274 Molecule (CD274) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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