| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | Parkinson Protein 2, E3 Ubiquitin Protein Ligase (PARK2) (aa 300-350) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | rat, mouse, human |
|---|
| Isotype | n/a |
|---|
| Format | immunogen affinity purified |
|---|
| Size | 40 μg |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA,Western Blotting (WB),Immunohistochemistry (IHC),Flow Cytometry (FACS) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Parkin, also known as PARKIN2, is a novel protein in Ubl conjugation pathway. Parkin functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include CCNE1, SYT11, GPR37, and STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP and SEPT5. Parkin may play a more general role in the ubiquitin proteasomal pathway by participating in the removal and/or detoxification of abnormally folded or damaged protein. The protein may protect neurons against alpha synuclein toxicity, proteasomal dysfunction, GPR37 accumulation, and kainate-induced excitotoxicity. Defects in PARK2 are a cause of Parkinson disease (PD).Parkin Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide within residues 300-350 of human parkin protein (Swiss Prot: O60260). |
|---|
| Immunogen | KLH-coupled synthetic peptide within AA 300-350 of human parkin protein |
|---|
| Other Names | Park|Prkn |
|---|
| Gene, Accession # | Gene ID: 56816 |
|---|
| Catalog # | ABIN1574065 |
|---|
| Price | |
|---|
| Order / More Info | Parkinson Protein 2, E3 Ubiquitin Protein Ligase (PARK2) (aa 300-350) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|