| 產(chǎn)品詳情 |
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| Antigenic Specificity | PD-L1 (CD274) |
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| Clone | RM320 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 μl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:200-1:500, Immunohistochemistry: 1:200-1:1000, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PD-L1 (CD274) Monoclonal Antibody (RM320). CD274, also commonly referred to as PDL1, is a ligand that binds with the receptor PD1, commonly found on T-cells, and acts to block T-cell activation. PD1 expression has been observed in a variety of cancers including melanoma and non-small cell lung cancer. The interaction of PD1/PDL1 is hypothesized to be a possible mechanism for the tumor to escape immune response. A number of checkpoint blockade inhibitors including pembrolizumab and nivolumab have been developed that target the PD1/PDL1 interaction in order to allow T-cells to recognize tumor cells without being deactivated by the tumor. |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 29126; Uniprot: Q9NZQ7 |
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| Catalog # | MA5-27896 |
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| Price | |
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| Order / More Info | PD-L1 (CD274) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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