| 產(chǎn)品詳情 |
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| Antigenic Specificity | Neuropilin |
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| Clone | 211H6.01 |
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| Host Species | Mouse |
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| Reactive Species | human, dog, swine |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100μg/50μg |
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| Concentration | n/a |
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| Applications | FACS, IHC, IP |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | We have generated a mAb that identifies human pDCs ex vivo. In blood, 211H6 antigen is highly expressed on IL3Ralpha+ BDCA-2+ CD11c- pDCs. It does not stain lymphocytes, monocytes, basophils and granulocytes. In vitro it is also expressed on monocyte-derived DCs. Upon maturtaion in IL-3 and CD40-L, or with influenza virus, 211H6 is maintained at the cell surface. In situ 211H6 recognizes some isolated cells in T cell zones of tonsils, lymphatic vessels and high endothelial venules. THe 211H6 antigen has been identified as BDCA-4. Neuropilin-1 is a membrane-bound co-receptor to a tyrosine kinase receptor for both vascular endothelial growth factor (VEGF) and semaphorin (SEMA3A) family members. Neuropilin 1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration and invasion. (Dzionek A and al., 2000 J. Immunol., 165: 6037-6046) |
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| Immunogen | n/a |
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| Other Names | Blood Dendritic Cell Antigen 4 protein |
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| Gene, Accession # | n/a |
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| Catalog # | DDX0440 |
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| Price | |
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| Order / More Info | Neuropilin Antibody from DENDRITICS SAS |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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