| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD182 |
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| Clone | 5E8/CXCR2 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, κ |
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| Format | PE-Cy7 conjugate |
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| Size | 25 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PE/Cy7 anti-human CD182 (CXCR2). CXCR2 is a 67-70 kD seven-transmembrane protein, also known as IL-8 receptor B (IL-8RB), CD182, and CD128b. It is a CXC chemokine receptor belongs to G protein-coupled receptor (GPCR) family. CXCR2 is expressed as homodimer or heterodimer with CXCR1 and found on granulocytes, NK cells, subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. CXCR2 mediates neutrophil activation and chemotaxis, megakaryocytic proliferation, and angiogenesis via binding its ligands including IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), and GRO-α,β,γ (CXCL1, CXCL2, CXCL3). |
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| Immunogen | Human CXCR2 transfected L1.2 cells |
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| Other Names | CD182, CXCR2, CD128b, IL-8RB, Type II IL-8 receptor |
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| Gene, Accession # | Gene ID: 3579 |
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| Catalog # | 320715 |
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| Price | |
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| Order / More Info | CD182 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 21807744 |
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| 產(chǎn)品資料 |
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