| 產(chǎn)品詳情 |
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| Antigenic Specificity | TRPC4AP |
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| Clone | 3G4 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a, kappa |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | ELISA: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TRPC4AP Monoclonal Antibody (3G4). Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1. |
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| Immunogen | n/a |
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| Other Names | TRPC4AP; transient receptor potential cation channel, subfamily C, member 4 associated protein; C20orf188; TRRP4AP; TRUSS; TRP4-associated protein; TRPC4-associated protein; short transient receptor potential channel 4 associated protein; tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein |
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| Gene, Accession # | Entrez: 26133; Uniprot: Q8TEL6 |
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| Catalog # | MA5-21614 |
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| Price | |
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| Order / More Info | TRPC4AP Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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