| 產(chǎn)品詳情 |
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| Antigenic Specificity | TRIF |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 μL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TRIF Polyclonal Antibody. Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. |
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| Immunogen | n/a |
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| Other Names | TICAM1;PRVTIRB; TRIF; TIR domain-containing adapter molecule 1; TIR domain-containing adapter molecule 1; Proline-rich, vinculin and TIR domain-containing protein B; TIR domain-containing adapter molecule 1; Putative NF-kappa-B-activating protein 502H; TI |
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| Gene, Accession # | Entrez: 106759, 148022; Uniprot: Q80UF7, Q8IUC6 |
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| Catalog # | PA5-35284 |
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| Price | |
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| Order / More Info | TRIF Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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