| 產(chǎn)品詳情 |
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| Product Name | INDY |
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| Description | DYRK1A/B inhibitor (IC50 values are 0.23 and 0.24 μM, for DYRK1B and DYRKA respectively). Binds at the ATP-binding cleft of the enzyme. Reverses aberrant tau-phosphorylation and rescues repressed calcineurin/NFAT signaling. Impairs the self-renewal capacity of subventricular zone neural stem cells. Also available as a prodrug, proINDY (Cat. No. 4998). Purity 98%. MW (observed): 235.3 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (1Z)-1-(3-Ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone |
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| Gene, Accession, CAS # | CAS: 1169755-45-6 |
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| Catalog # | 4997/10 |
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| Price | |
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| Order / More Info | INDY from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 25751815, 25878110, 27483355 |
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