| 產(chǎn)品詳情 |
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| Antigenic Specificity | VISTA |
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| Clone | B7H5DS8 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | PE-Cyanine7 conjugate |
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| Size | 100 Tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 5 μL (0.125 μg)/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | VISTA Monoclonal Antibody (B7H5DS8), PE-Cyanine7, eBioscience?. VISTA (V-domain Ig containing suppressor of T-cell activation), also known as B7-H5 or PD-1H, is a product of the VSIR gene. Although VISTA bears sequence homology to PD-L1 it has a different expression pattern. In both mouse and humans, VISTA is expressed predominantly on hematopoietic cells with the highest densities on myeloid cells, and lower levels on T cells. It is usually absent on B cells. VISTA expressed by antigen presenting cells has been shown to directly suppress proliferation and cytokine production of CD4 and CD8 T cells, making it a target for cancer immunotherapy. The reported ligands of VISTA include CD28H, VSIG-3 and VSIG-8. |
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| Immunogen | n/a |
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| Other Names | B7-H5, PD-H1, Gi24, Dies1, SISP1, C10orf54, PD-1H |
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| Gene, Accession # | Entrez: 64115; Uniprot: Q9H7M9 |
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| Catalog # | 25-1088-42 |
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| Price | |
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| Order / More Info | VISTA Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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