| 產(chǎn)品詳情 |
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| Product Name | Sunitinib Malate (Sutent) |
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| Description | Sunitinib is a potent inhibitor of CSF-1 receptor kinase in an enzyme assay, with an IC50 of 7 nM, and inhibits receptor phosphorylation in a cellular assay with an IC50 of 61 nM. Sunitinib inhibits SCF-induced phosphotyrosine levels on KIT (IC50 = 1 - 10 nM) and reduced SCF-stimulated ERK1/2 phosphorylation with an IC50 value consistent with that for inhibition of KIT phosphotyrosine levels. Sunitinib also inhibited SCF-stimulated proliferation in NCI-H526 cells (IC50 = 2 nM). MW: 532.56. Purity ≥99% by HPLC |
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| Size | 100 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Sunitinib Maleate, SU-11248, Sutent, PHA-290940AD, PNU-290940AD |
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| Gene, Accession, CAS # | CAS: 341031-54-7 |
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| Catalog # | 1611-100 |
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| Order / More Info | Sunitinib Malate (Sutent) from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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