| Edit |   |
|---|
| Antigenic Specificity | Thyroid Hormone Receptor, alpha (THRA) (N-Term) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | affinity purified |
|---|
| Size | 25 μL |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blotting (WB),ELISA |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Thyroid hormone receptor alpha is a nuclear hormone receptor with high affinity for the hormone triiodo-thyronine. THRA is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having a certain extent of redundancy, may mediate different functions of thyroid hormone. THRA interacts with NCOA3 and NCOA6 co-activators, leading to a strong increase in transcription of target genes. THRA is localized within the nucleus and has been found to exist as 4 isoforms originating from alternative splicing variants. Isoform 1 has a distinct C-terminus compared to isoform 2.Synonyms: Thyroid hormone receptor alpha Nuclear receptor subfamily 1 group A member 1 c-erbA-alpha c-erbA-1 V-erbA-related protein 7 EAR-7 |
|---|
| Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the amino terminus of human THRA isoform 1 protein.Immunogen Type: Peptide |
|---|
| Other Names | EAR1|THRA1|THRAL|ear-1|hRev|ERBA1|Thra1|6430529J03Rik|AW259572|Erba|Nr1a1|Rvr|T3R[a]|T3Ralpha|Thra2|Thra|nr1a1|thra1|TR[a]1|thra|thral|tra|tra1|wu:fb59g07|Nr1a2|T3R[b]|T3Rbeta|Thrb1|Thrb2|c-erbAbeta|AR7|CHNG6|EAR7|ERB-T-1|ERBA|NR1A1|THRA2|c-ERBA-1|C-ERBA-ALPHA|C-ERBA ALPHA1|TRalpha|c-erba|erba|nr1a1-A|thra-A|THR |
|---|
| Gene, Accession # | Gene ID: 7067 |
|---|
| Catalog # | ABIN964884 |
|---|
| Price | |
|---|
| Order / More Info | Thyroid Hormone Receptor, alpha (THRA) (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|