| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | AV 412 |
|---|
| Description | Potent inhibitor of EGFR, ErbB2 and Abl receptor tyrosine kinases (IC50 values are 0.5-2, 19 and 41 nM, respectively). Also weak inhibitor of FLT1 and Src. Inhibits EGFR and ErbB2 autophosphorylation in vitro in NSCLC and T-47D breast cancer cell lines, respectively. Inhibits tumor growth of EGFR-overexpressing A431 and ErbB2 overexpressing BT-474 tumor xenografts in mice. Purity 98%. MW (observed): 507 |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-methyl-3-(4-methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]-2-propenamide |
|---|
| Gene, Accession, CAS # | CAS: 451492-95-8 |
|---|
| Catalog # | 4397/10 |
|---|
| Price | |
|---|
| Order / More Info | AV 412 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|