| 產(chǎn)品詳情 |
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| Product Name | TAK 242 |
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| Description | Toll-like receptor 4 (TLR4) signaling inhibitor. Binds to intracellular domain of TLR4. Inhibits LPS-induced cytokine production in vitro (IC50 values are 1.3, 1.3 and 3.2 nM for IL-6, TNFα and NO production). Reduces lesion volume in a mouse model of cerebral cavernous malformations (CCMs). Also attenuates increased cytokine levels in a mouse sepsis model, when given in combination with ceftazidime. Cell permeable. Purity 98%. MW (observed): 361.82 |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (R)-Ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate |
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| Gene, Accession, CAS # | CAS: 243984-11-4 |
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| Catalog # | 6587/5 |
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| Price | |
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| Order / More Info | TAK 242 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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