| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | Ailanthone |
|---|
| Description | Potent androgen receptor (AR) inhibitor (IC50 = 69 nM). Disrupts the AR-chaperone complex by binding p23 and blocking AR interaction with HSP90 causing UPS degradation of AR. Inhibits Huh7 cancer cell growth via G0/G1 cell cycle arrest and apoptosis in vitro and in vivo. Inhibits growth and metastasis of certain prostate cancer cell lines. Orally bioavailable. Purity 98%. MW (observed): 376.4 |
|---|
| Size | 5 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | (1β,11β,12α)-11,20-Epoxy-1,11,12-trihydroxypicrasa-3,13(21)-diene-2,16-dione |
|---|
| Gene, Accession, CAS # | CAS: 981-15-7 |
|---|
| Catalog # | 6161/5 |
|---|
| Price | |
|---|
| Order / More Info | Ailanthone from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|