| 產(chǎn)品詳情 |
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| Product Name | AG-14361 |
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| Description | A PARP1 inhibitor (Ki = 6.3 nM); inhibits PARP1 activity in permeabilized and intact SW620 cells (IC50s = 29 and 14 nM, respectively); potentiates the growth inhibitory effects of temozolomide and topotecan in vitro at 0.4 μM; also inhibits cell growth in a PARP1-independent manner (GI50s = 66 and 65 μM for cells derived from PARP1+/+ and PARP1-/- mice, respectively); leads to tumor regression in an SW620 mouse xenograft model when used in combination with temozolomide |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AG14361 PARP-1 SW-620 A-2480 CP-70 HCT-116 |
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| Gene, Accession, CAS # | CAS: 328543-09-5 |
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| Catalog # | 24677-1 |
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| Price | |
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| Order / More Info | AG-14361 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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