| 產(chǎn)品詳情 |
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| Product Name | SSR 240612 |
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| Description | A selective, non-peptide bradykinin B1 receptor antagonist (Kis = 0.48-0.73 and 358-481 nM for B1 and B2 receptors, respectively); inhibits the contraction of rabbit aorta and rat ileum induced by des-Arg9-BK ex vivo; reduces tissue damage and neutrophil accumulation in a rat model of splanchnic artery occlusion/reperfusion-induced intestinal injury; inhibits des-Arg9-BK-induced paw edema in mice at 3 and 10 mg/kg; reduces fibrosis in a unilateral ureteral obstruction mouse model of kidney fibrosis; reduces mean arterial blood pressure in two rat models of hypertension; reduces plasma glucose and insulin levels in a glucose-fed rat model of insulin resistance; exhibits analgesic properties in several rodent models of hyperalgesia |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 465539-70-2 SSR240612 |
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| Gene, Accession, CAS # | CAS: 464930-42-5 |
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| Catalog # | 25544-10 |
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| Order / More Info | SSR 240612 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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