| 產(chǎn)品詳情 |
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| Product Name | PF 3644022 |
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| Description | Potent, ATP-competitive inhibitor of mitogen-activated protein kinase (MAPK)-activated protein kinase-2 (MK2) (IC50 = 5.2 nM; Ki = 3 nM). Inhibits tumor necrosis factor α (TNFα) production in U937 monocytic cells and peripheral blood mononuclear cells (PBMCs) (IC50 = 160 nM); exhibits oral efficacy in acute and chronic inflammatory models. Purity 98%. MW (observed): 374.46 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (10R)-9,10,11,12-Tetrahydro-10-methyl-3-(6-methyl-3-pyridinyl)-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one |
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| Gene, Accession, CAS # | CAS: 1276121-88-0 |
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| Catalog # | 4279/10 |
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| Price | |
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| Order / More Info | PF 3644022 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 26017782, 28506461 |
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| 產(chǎn)品資料 |
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