| 產(chǎn)品詳情 |
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| Product Name | SIRT5 (GST-tagged), Human recombinant |
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| Description | The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human sirtuins, which have been designated SIRT1-7. SIRT5 is located in the mitochondrial matrix and its functions are largely still being elucidated, however a few promising substrates have been studied. SIRT5 has been shown to deacetylate carbamoyl phosphate synthetase 1 (CSP1), activating the enzyme to catalyze the first step of the urea cycle. CSP1 is important in the detoxification of excess ammonia that can accumulate during fasting. Cytoch |
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| Size | 50 μg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | NAD-dependent Deacetylase 5; SIR2-like Protein 5; SIR2L5; Sirtuin 5; Silent Information Regulator 5 |
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| Gene, Accession, CAS # | SIRT5, Gene ID: 23408, Accession: Q9NXA8 |
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| Catalog # | 7674-50 |
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| Price | |
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| Order / More Info | SIRT5 (GST-tagged), Human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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