| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | Norrie Disease (Pseudoglioma) (NDP) peptide |
|---|
| Description | NDP activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. NDP plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. NDP acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). |
|---|
| Size | 100 μg |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
|---|
| Other Names | EVR2|FEVR|ND|evr2|fevr|xnorrin|Ndph|RGD1563968 |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | ABIN937500 |
|---|
| Price | |
|---|
| Order / More Info | Norrie Disease (Pseudoglioma) (NDP) peptide from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|