| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | huntingtin (specific for expanded polyQ by western blot) |
|---|
| Clone | MW1 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG2b |
|---|
| Format | supernatant |
|---|
| Size | 1.0 ml |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA, FACS, Function Blocking, Immunofluorescence, Immunoprecipitation, Western Blot |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Epitope: N-terminal, polyQ. MW1 is specific for the elongated polyQ stretch through which mHtt aggregates. The epitope is hidden in aggregates. This antibody is also known as anti-polyQ. Appears to recognize an altered conformation of the polyQ domain generated as the polyQ domain of Htt increases in length. Time-resolved Foerster resonance energy transfer (TR-FRET) assay has been developed using MW1 to assay soluble huntingtin. PMID: 22365609 23966247 23626768 23100324 22984513. RRID:AB_528290 |
|---|
| Immunogen | Recombinant DRPLA-19Q/GST fusion protein: Partial protein |
|---|
| Other Names | HD, IT15 |
|---|
| Gene, Accession # | HTT, Gene ID: 3064, UniProt: P42858 |
|---|
| Catalog # | MW1 |
|---|
| Price | |
|---|
| Order / More Info | huntingtin (specific for expanded polyQ by western blot) Antibody from DEVELOPMENTAL STUDIES HYBRIDOMA BANK |
|---|
| Product Specific References | PubMed: 11719267, 11719267, 19690053, 19491400, 22037470, 11719267, 24798518, 19491400, 20086007, 22919566, 26174131, 20086007, 11719267, 19491400, 26174131, 11792860 |
|---|
| 產(chǎn)品資料 |
|
|