| 產(chǎn)品詳情 |
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| Product Name | Complement factor I, Human, Natural |
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| Description | Complement Factor I (fI) is a protein of the complement system, first isolated in guinea pig serum that regulates complement activation by cleaving cell-bound or fluid phase C3b and C4b. Factor I deficiency in turn leads to low levels of complement component 3 (C3) in plasma, due to unregulated activation of the complement alternative pathway, and it has been associated with recurrent bacterial infections in children; more recently, mutations in the Factor I gene have been shown to be implicated in development of Haemolytic Uremic Syndrome, a renal disease also caused by unregulated complement activation. |
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| Size | 100 μg |
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| Concentration | 0.1 ml of approximately 1 mg/ml purified natural human Factor-I isolated from healthy blood donors, in Phosphate buffered saline, pH 7.2. The blood donors have been tested and found negative for various viruses (see table: Human blood test results). The exact protein concentration and functional activity is indicated on the label. |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | HC2131 |
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| Order / More Info | Complement factor I, Human, Natural from HYCULT BIOTECH |
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| Product Specific References | n/a |
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