| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | [D-Arg1,D-Phe5,D-Trp7,9,Leu11]Substance P (trifluoroacetate salt) |
|---|
| Description | A broad-spectrum neuropeptide antagonist with anticancer activity; analog of substance P; blocks intracellular calcium increases induced by vasopressin, bradykinin, gastrin, and galanin in H-510 SCLC cells; blocks vasopressin- and bradykinin-induced MAPK signaling in H-510 SCLC cells in a concentration-dependent manner; inhibits DNA synthesis in a panel of cancer cell lines (IC50s = 20-50 μM); reduces colony formation of HC12, ICR-SC112, HX149, and NCI-H226 cancer cells in vitro (IC50s = 0.5-6.5 μM); inhibits tumor growth in HC12 and ICR-SC112 SCLC mouse xenograft models (2.1 μg, s.c.) , |
|---|
| Size | 1 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | D-Phe5SP|L-756,867|SPD-D |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 24829-1 |
|---|
| Price | |
|---|
| Order / More Info | [D-Arg1,D-Phe5,D-Trp7,9,Leu11]Substance P (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|