| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD171 |
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| Clone | L1-OV198.5 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a, κ |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), Immunofluorescence Microscopy (IF), Western Blot (WB), IHC-F, IP |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human CD171 (L1CAM). CD171, also known as L1CAM or L1, is a transmembrane glycoprotein. It is a 200-220 kD neuronal cell adhesion molecule and a member of the L1 protein family belonging to the immunoglobulin superfamily. This cell adhesion molecule plays an important role in nervous system development, including neuron-neuron adhesion, signal transduction, axon guidance, cell migration and differentiation. CD171 also has a strong implication in treatment-resistanct cancers. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. |
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| Immunogen | SKOV-3 ovarian carcinoma cells. |
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| Other Names | CAML1, HSAS, HSAS1, MASA, MIC5, N-CAM-L1, N-CAML1, S10, SPG1, L1CAM, Neural cell adhesion molecule L1 |
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| Gene, Accession # | Gene ID: 3897 |
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| Catalog # | 371602 |
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| Price | |
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| Order / More Info | CD171 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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